Faculty Profile

Sonia Kupfer
Section of Gastroenterology
Professor of Medicine
Referring Physician Access Line: 1-877-DOM-2730
Director, Physician Scientist Development Program

Academic Interests

Dr. Kupfer is a physician-scientist with clinical and research interests in gastrointestinal cancers and health disparities. She serves as Director of the Gastrointestinal Cancer Risk and Prevention clinic at UChicago Medicine. As an adult gastroenterologist, Dr. Kupfer also maintains a strong collaborative relationship with the UChicago Celiac Disease Center. She graduated from Yale University and completed her medical training including Chief Residency and Gastroenterology fellowship at the University of Chicago. She is an Associate Professor and Associate Section Chief for Educational Programming. She is co-PI of the GI Section’s T32 training grant and a Core Director for the Digestive Diseases Research Center grant. She serves as Chair of the Cancer Health Disparities working group in the UChicago Comprehensive Cancer Center. Dr. Kupfer is funded by the NIH/NCI and American Gastroenterological Association (AGA) to study host-environment interactions using human colonic organoids from diverse populations. Dr. Kupfer also has philanthropic funding to support the UChicago pancreatic cancer surveillance program. Dr. Kupfer is Past-President of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer and currently serves on the Education committee. She is a core faculty member for the City of Hope’s Intensive Course on Cancer Genomics. She serves on several committees for the AGA and is on the Editorial Board for Gastroenterology. In 2017, Dr. Kupfer was awarded the Division of Biological Sciences Diversity and Inclusion Junior award and the Joseph B. Kirsner Mentorship Award. In 2019, Dr. Kupfer was awarded the AGA Young Investigator Award. Dr. Kupfer was recently selected as a mentor for the AGA Future Leaders program.

Clinical Interests

Diagnosis and treatment of patients with genetic disorders such as hereditary gastrointestinal cancer syndromes and celiac disease.


For a complete list of publications click here:


  • BA, 1996, Yale University, German Studies
  • MD, 2001, University of Chicago, Medicine
  • Residency, 2004, University of Chicago
  • Chief Resident, 2005, University of Chicago
  • Fellowship, 2008, University of Chicago, Gastroenterology