Faculty Profile

Eve Van Cauter
Section of Endocrinology, Diabetes and Metabolism
Professor of Medicine
Emeritus, Frederick H. Rawson Professor

Academic Interests

Dr. Van Cauter’s major interests are the role of sleep in the regulation of hormonal release and metabolism and the characterization of the abnormal sleep patterns found in a variety of conditions, including aging. She uses analyses of temporal patterns of hormonal secretion to study the functional significance of sleep and circadian rhythmicity on endocrine function in normal and pathological conditions. In recent years, Dr. Van Cauter has also led a major research program evaluating the impact of decreased sleep duration and quality on the risk of obesity and diabetes and the possible endocrine and metabolic benefits of improved sleep quality in older adults.

Clinical Interests



  • Spiegel K, Sheridan JF, and Van Cauter E. Effect of sleep deprivation on response to immunization. Jama, 2002. 288(12): p. 1471-2.
  • Spiegel K, Leproult R, Tasali E, Penev P, and Van Cauter E. Sleep curtailment results in decreased leptin levels, elevated ghrelin levels and increased hunger and appetite. Annals Int Med,141(11):846-850, 2004.
  • Spiegel K, Leproult R, Van Cauter E. Impact of a sleep debt on metabolic and endocrine function. The Lancet, 354: 1435-1439, 1999.
  • Van Cauter E, Leproult R and Plat L. Age-related changes in slow wave sleep and REM sleep and relationship with growth hormone and cortisol levels in healthy men. JAMA 284: 861-868, 2000.
  • Spiegel K, Leproult R, L’Hermite-Balériaux M, Copinschi G, Penev P and Van Cauter E. Impact of sleep duration on the 24-hour leptin profile: relationships with sympatho-vagal balance, cortisol and TSH. J Clin Endocrinol Metab, 89(11):5762-5771, November 2004.


  • BS, 1970, University Libre de Bruxelles, Physics
  • MS, 1973, University Libre de Bruxelles, Actuarial Sciences
  • PhD, 1977, University Libre de Bruxelles, Biophysics