Faculty Profile

Mark Ratain
Section of Hematology / Oncology
Professor of Medicine
Referring Physician Access Line: 1-877-DOM-2730
Leon O. Jacobson Professor of Medicine;Director, Center for Personalized Therapeutics; Associate Director for Clinical Sciences, Comprehensive Cancer Center

Academic Interests

Dr. Ratain is interested in the pharmacogenetics of anticancer agents and phase I and phase II drug studies. Dr. Ratain’s research is focused on the metabolism of specific anticancer agents. He has demonstrated the critical importance of genetic variants in determining variability in the pharmacogenetics and toxicity of certain anticancer drugs. His research has become a model for understanding variability in response to newer targeted drugs.

Clinical Interests

New drug development, phase I and phase II drug development, advanced solid tumors.


For a complete list of publications click here:


  • BA, 1976, Harvard University, Biochemical Sciences
  • MD, 1980, Yale University,
  • Residency, 1983, Johns Hopkins University, Internal Medicine
  • Fellowship, 1986, The University of Chicago, Hematology/Oncology