Faculty Profile

Bana Jabri
Section of Gastroenterology
Professor of Medicine
bjabri@bsd.uchicago.edu
Referring Physician Access Line: 1-877-DOM-2730
Sara and Harold Lincoln Thompson Distinguished Service Professor; Vice Chair for Research (Basic); Chair, Committee on Immunology; Director, Center for Human Immunology

Academic Interests

To face multiple environmental aggressions from pathogens and dietary elements, the intestinal mucosa is colonized by an army of mobile antigen-specific effector T lymphocytes and by a distinct population of resident T cells involved in the tissue stress response. The intestine is in fact the only mammalian site allowing ready access to the effector phase of immune responses in the tissue microenvironment. Dr. Jabri’s labaoratory overall interest is mucosal and innate immunity, and more specifically the interplay between the immune system and mucosal surfaces. They have a particular interest in intestinal inflammatory diseases, with a focus on celiac disease and inflammatory bowel disease. Her laboratory has expertise in human immunology and is developing mouse models of intestinal inflammation.They use a range of molecular and cellular approaches, including the study of signal transduction, cellular immunology and genetic engineering of mouse models, to study the developmental and functional aspects of immune function in the mouse and human intestine. These studies address basic immunological questions and may lead to novel insights into the mechanisms of inflammatory intestinal diseases and the development of new therapeutic strategies.
 

Clinical Interests

 

Publications

For a complete list of publications click here:

Training

  • BA, 1986, Universite Paris VII, Biochemistry
  • Fellowship, 1990, Hôpital Necker, Paris, France, Clinical Immunology & Immunodeficiency
  • MD, 1991, Institut Pasteur
  • Residency, 1991, Assistance Publique Hôpitaux de Paris
  • Fellowship, 1994, National Institutes of Health, Molecular Biology and Allergology
  • PhD, 1996, Universite Paris VII, Immunology