Faculty Profile


Matthew Brady
Section of Endocrinology, Diabetes and Metabolism
Associate Professor of Medicine
mbrady@medicine.bsd.uchicago.edu

Academic Interests

The Brady lab in the Kovler Diabetes Center has a long standing interest in studying adipocyte biology, energy metabolism and insulin sensitivity. The lab is currently focused on two collaborative transdisciplinary projects: 1) determining the impact of altered sleep quality, circadian behavior and bariatric on cellular and systemic insulin sensitivity in humans; 2) studying the role of chronic social isolation on mammary gland development, mammary adipose tissue biology and the progression of triple negative breast cancer in rodents.
 

Clinical Interests

 

Publications

  • Broussard, J., Ehrmann, D.E., Van Cauter, E., Tasali, E and Brady, M.J. (2012) Impaired insulin signaling in human adipocytes following experimental sleep disturbance. Ann. Int. Med. 157, 549-557 PMCID: PMC4435718
  • Volden, P.A., Wonder, E.L., Ye, H., Kocherginsky, M., Smith, E., Kregel, S., McClintock, M.K., *Brady, M.J. and *Conzen, S.D. (2013) Chronic social isolation is associated with metabolic gene expression changes specific to mammary adipose tissue. Cancer Prev. Res. 6,634-645 Cover article. PMCID: PMC3881320
  • Carmean, C.M., Cohen, R.N. and Brady M.J. (2014) Systemic regulation of adipose metabolism. Biochim Biophys Acta. 1842,424-430
  • Carmean, C.C., Haung, Y-G. H. and Brady, M.J. (2016) Glycogen repletion in brown adipose tissue upon refeeding is primarily driven by allosteric enzymatic regulation. PLoS One 11, e0156148 PMCID: PMC4877058
  • Volden, P.A., Skor, M.N., Johnson, M.B., Singh, P., Patel, F.N., McClintock, M.K., *Brady, M.J. and *Conzen, S.D. (2016) Mammary adipose tissue-derived lysophospholipids promote estrogen receptor-negative mammary epithelial cell proliferation. Cancer Prev. Res. 9, 367-378 PMCID: PMC4854771
For a complete list of publications click here:

Training

  • BA, 1987, The University of Chicago, Biological Sciences
  • PhD, 1994, The University of Chicago, Pharmaceutical and Physiological Sciences
  • Fellowship, 1997, Parke-Davis Pharmaceutical Research, Cell Biology