Faculty Profile


Orly Kohn
Section of Nephrology
Associate Professor of Medicine
okohn@medicine.bsd.uchicago.edu
Referring Physician Access Line: 1-877-DOM-2730
Medical Director of the Home Dialysis Program

Academic Interests

Dr. Orly Kohn is the Director of the Home Dialysis Unit and investigates factors which promote retention of patients on peritoneal dialysis, extended technique survival and continuation of PD post abdominal surgeries. Dr. Kohn is a national leader in the area of home dialysis and has more than 15 years of experience in this field. She leads the fellowship training program on home dialysis with a full year dedicated track to this area of inquiry. Dr. Kohn has other research interests including application of functional MRI in moderate chronic kidney disease to predict disease progression. fMRI using the BOLD technique allows for accurate assessment of oxygen utilization under conditions of tubular transport blockade, a phenomena that reduces renal tubular energy requirements. Dr. Kohn has also developed an educational curricula for training in native and transplant kidney biopsies that involve didactic lectures, utilization of the simulation center and renal phantoms and structured faculty oversight involving both Nephrology and Interventional Radiology.
 

Clinical Interests

Diabetic nephropathy, optimizing care of the pre-ESRD patient, acid base and electrolyte abnormalities, home hemodialysis and peritoneal dialysis.
 

Publications

  • Consistency of Multiple Renal Functional MRI Measurements Over 18 Months. Li LP, Thacker J, Li W, Tan H, Wang C, Kohn O, Sprague S, Prasad P. J Magn Reson Imaging. 2018 Mar 8. doi: 10.1002/jmri.26001. [Epub ahead of print]
  • Evaluation of Renal Blood Flow in Chronic Kidney Disease Using Arterial Spin Labeling Perfusion Magnetic Resonance Imaging. Li LP, Tan H, Thacker JM, Li W, Zhou Y, Kohn O, Sprague SM, Prasad PV. Kidney Int Rep. 2017 Jan;2(1):36-43. doi: 10.1016/j.ekir.2016.09.003. Epub 2016 Sep 13.
  • Three-Stream, Bicarbonate-Based Hemodialysis Solution Delivery System Revisited: With an Emphasis on Some Aspects of Acid-Base Principles. Lew SQ, Kohn OF, Cheng YL, Kjellstrand CM, Ing TS. Artif Organs. 2017 Jun;41(6):509-518. doi: 10.1111/aor.12947. Review.
  • Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study. Parsa A, Kanetsky PA, Xiao R, Gupta J, Mitra N, Limou S, Xie D, Xu H, Anderson AH, Ojo A, Kusek JW, Lora CM, Hamm LL, He J, Sandholm N, Jeff J, Raj DE, Böger CA, Bottinger E, Salimi S, Parekh RS, Adler SG, Langefeld CD, Bowden DW; FIND Consortium, Groop PH, Forsblom C, Freedman BI, Lipkowitz M, Fox CS, Winkler CA, Feldman HI; and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. J Am Soc Nephrol. 2017 Mar;28(3):923-934. doi: 10.1681/ASN.2015101152. Epub 2016 Oct 11.
  • Selecting SNPs informative for African, American Indian and European Ancestry: application to the Family Investigation of Nephropathy and Diabetes (FIND). Williams RC, Elston RC, Kumar P, Knowler WC, Abboud HE, Adler S, Bowden DW, Divers J, Freedman BI, Igo RP Jr, Ipp E, Iyengar SK, Kimmel PL, Klag MJ, Kohn O, Langefeld CD, Leehey DJ, Nelson RG, Nicholas SB, Pahl MV, Parekh RS, Rotter JI, Schelling JR, Sedor JR, Shah VO, Smith MW, Taylor KD, Thameem F, Thornley-Brown D, Winkler CA, Guo X, Zager P, Hanson RL; FIND Research Group. BMC Genomics. 2016 May 4;17:325. doi: 10.1186/s12864-016-2654-x.
For a complete list of publications click here:

Training

  • BS, 1975, University of Illinois, Biology
  • MD, 1979, University of Illinois,
  • Residency, 1982, University of Illinois, Internal Medicine
  • Fellowship, 1983, University of Illinois, Nephrology
  • Fellowship, 1987, University of Connecticut, Nephrology