Faculty Profile

Anne Sperling
Section of Pulmonary / Critical Care
Professor of Medicine
Associate Vice Chair for Research Faculty Director, Immunological Applications Core Facility;

Academic Interests

Dr. Sperling’s laboratory is investigating the role of co-receptors in T cell function. Understanding these key regulators of T cell responses is essential for determining mechanisms involved in the development of asthma and other lung diseases. Areas of emphasis include 1) ICOS regulation of Th2 inflammation in asthma models; 2) genetic variation of the ICOS gene in human allergy; 3) CD43 regulation of T cell activation; 4) Fas regulation of clearance of Th2 mediated inflammation.

Clinical Interests



For a complete list of publications click here:


  • AB, 1984, Smith College, Biology
  • PhD, 1990, Tufts University, Immunology
  • Fellowship, 1994, The University of Chicago, Committee on Immunology