Faculty Profile
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Antonio Bianco
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Section of Endocrinology, Diabetes and Metabolism
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Professor of Medicine
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abianco1@uchicago.edu
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Referring Physician Access Line: 1-877-DOM-2730
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Academic Interests
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Dr. Bianco is interested in understanding the aspects of thyroid hormone action that involve the deiodinases D1, D2 and D3. He investigates the physiological roles played by these enzymes and their involvement in disease mechanisms. Knowledge obtained from these studies will help develop therapies that preserve thyroid hormone homeostasis in patients with hypothyroidism.
Clinical Interests
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Treatment of hypothyroidism
Publications
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Fonseca TL, Fernandes GW, McAninch EA, Bocco BMLC, Abdalla SM, Ribeiro MO, Mohácsik P, Fekete C, Li D, Xingh X, Wang T, Gereben B, Bianco AC. Perinatal Deiodinase 2 Expression in Hepatocytes Defines Epigenetic Susceptibility to Liver Steatosis and Obesity. Proc Nat Acad Sci 2015; 112(45):14018-23
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Lartey LJ, Werneck-de-Castro JP, Sullivan IS, Unterman TG, Bianco AC. Coupling Between Nutrient Availability and Thyroid Hormone Activation. J Biol Chem 2015; 290(51):30551-61
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Fernandes GW, Bocco BML, Fonseca TL, McAninch EA, Jo S, Lartey LJ, O-Sullivan IS; Unterman TG; Preite NZ, Voigt R; Forsyth CB; Keshavarzian A, Sinkó R, Goldfine AB, Patti ME, Ribeiro MO, Gereben B, Bianco AC. The FoxO1-inducible transcriptional repressor Zfp125 causes hepatic steatosis and hypercholesterolemia. Cell Rep 2018 Jan; 22(2):523-534
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McAninch EA, Rajan K, Evans D, Jo S, Chaker L, Peeters R, Bennett D, Mash D, Bianco AC. A Common DIO2 Polymorphism and Alzheimer's Disease Dementia in African And European Americans. J Clin Endocrinol Metab. 2018 May 1;103(5):1818-1826.
For a complete list of publications click
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Training
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BS, 1977, Dante Alighieri College,
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MD, 1983, Santa Casa School of Medicine,
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MS, 1985, Univeristy of Sao Paulo, Human Physiology
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PhD, 1988, University of Sao Paulo, Human Physiology