Details - University of Chicago Medicine Faculty Profiles

Fotini Gounari

Section of Rheumatology

Associate Professor of Medicine

fgounari@medicine.bsd.uchicago.edu

Academic Interests

Dr. Gounari is interested in signal transduction pathways that are involved in the development of hematopoietic stem cells into the T-cell lineage and deregulations that lead to leukemia. A major focus of research is the pre-T-Cell Receptor, that triggers the expansion and differentiation of immature thymocytes. Her work has demonstrated a cross talk of preTCR signaling with the Wnt/beta-catenin and Notch cascades. Both Wnt/beta-catenin and Notch have been directly linked with human cancer. Dr. Gounari is currently studying the physiological versus pathological interactions of these pathways in developing versus transformed thymocytes.

Clinical Interests

Publications

For a complete list of publications click here:

Training

B.Sc., 1983, Aristotelian University,Thessaloniki, Biology
PhD, 1986, National Institute for Medical Research, London, UK, Genetics
D.Sc., 1998, Rene Descartes University,Paris, Immunology