Faculty Profile
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Fotini Gounari
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Section of Rheumatology
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Associate Professor of Medicine
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fgounari@medicine.bsd.uchicago.edu
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Academic Interests
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Dr. Gounari is interested in signal transduction pathways that are involved in the development of hematopoietic stem cells into the T-cell lineage and deregulations that lead to leukemia. A major focus of research is the pre-T-Cell Receptor, that triggers the expansion and differentiation of immature thymocytes. Her work has demonstrated a cross talk of preTCR signaling with the Wnt/beta-catenin and Notch cascades. Both Wnt/beta-catenin and Notch have been directly linked with human cancer. Dr. Gounari is currently studying the physiological versus pathological interactions of these pathways in developing versus transformed thymocytes.
Clinical Interests
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Publications
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For a complete list of publications click
here:
Training
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B.Sc., 1983, Aristotelian University,Thessaloniki, Biology
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PhD, 1986, National Institute for Medical Research, London, UK, Genetics
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D.Sc., 1998, Rene Descartes University,Paris, Immunology