Faculty Profile


Michael Broman
Section of Cardiology
Assistant Professor of Medicine
Michael.Broman@uchospitals.edu
Referring Physician Access Line: 1-877-DOM-2730

Academic Interests

Dr. Broman’s academic research focus is on the role of developmental transcriptional regulators and other genetic factors in the pathogenesis of atrial fibrillation, a common abnormal heart rhythm affecting a large proportion of the general population. His laboratory utilizes animal models and human tissue studies to address questions regarding the roles of, primarily, the GATA4/FOG-2 axis in atrial fibrillation and cardiac failure.
 

Clinical Interests

Cardiac Arrhythmias;Heart Failure; Pacemakers/Defibrillators;Cardiovascular Genetics
 

Publications

  • Vogel SM, Orrington-Myers J, Broman M, Malik AB. 2006. De novo ICAM-1 synthesis in the mouse lung: model of assessment of protein expression in lungs. Am J Physiol Lung Cell Mol Physiol. 291(3):L496-501. PMID: 16714332
  • Rangarajan D Nadadur, Michael T Broman, Bastiaan Boukens, Stefan Mazurek, Malou van den Boogaard, Jenna Bekeny, Chih-wei Wu, Min Zhang, James F Martin, Vincent Christoffels, Igor Efimov, Elizabeth M McNally, Christopher R Weber, Ivan P. Moskowitz. A TBX5-PITX2 incoherent feed forward loop modulates atrial rhythm. In Press. Science Translational Medicine 2016
  • Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC. 2014. FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. Sep 6. S0012-1606(14)00421-7. PMID: 25196150
  • Osbourne A, Calway T, Broman M, McSharry S, Earley J, Kim GH. 2014. Downregulation of connexin43 by microRNA-130a in cardiomyocytes results in cardiac arrhythmias. J Mol Cell Cardiol. May 10;74C:53-63. PMID: 24819345
  • Michael T. Broman, Panos Kouklis, Xiaopei Gao, Ramaswamy Ramchandran, Radu F. Neamu, Richard D. Minshall, Asrar B. Malik. 2006. Cdc42 Regulates Adherens Junction Stability and Endothelial Permeability by Inducing Alpha-Catenin Interaction With the Vascular Endothelial Cadherin Complex. Circ. Res.;98:73. PMID: 16322481
For a complete list of publications click here:

Training

  • BA, 1999, University of Iowa, Biochemistry
  • PhD, 2007, University of Illinois-Chicago, Pharmacology
  • MD, 2007, University of Illinois College of Medicine,
  • Residency, 2009, The University of Chicago, Internal Medicne
  • Fellowship, 2012, The University of Chicago, Cardiovascular Disease
  • Fellowship, 2013, The University of Chicago, Clinical Cardiac Electrophysiology